Shy, sensitive artist Patience Philips (HALLE BERRY) can’t seem to stop apologizing for her own existence. A meek people-pleaser, she works as a graphic designer for mammoth cosmetics company Hedare Beauty, run by the despotic George Hedare (LAMBERT WILSON) and his supermodel wife, Laurel (SHARON STONE). When Patience inadvertently stumbles upon a sinister secret about the company’s soon-to-be-released revolutionary anti-aging product, she finds herself trapped in the middle of a dangerous conspiracy. But at her darkest moment, Patience is saved – reborn with the strength, speed, agility and ultra-keen senses of a cat.

Guided by a mysterious mentor named Ophelia Powers (FRANCES CONROY), Patience soon begins to explore her newfound prowess and feline intuition, as well as her history – she is the latest in a long line of women who have been chosen throughout the ages to be gifted with these extraordinary powers. With her newly-gained knowledge and strength she becomes Catwoman, a strong, sleek and stealthy creature delicately balancing on the thin line between good and bad.

Catwoman’s adventures begin as she goes on the prowl to settle a few scores, but her double life is quickly complicated by Patience’s burgeoning relationship with stalwart detective Tom Lone (BENJAMIN BRATT). Lone is falling for Patience, but he cannot shake his fascination with the feline fatale who appears to be responsible for a string of crimes plaguing the city.

As she learns how to exploit her superhuman powers, Catwoman becomes stronger, faster and a greater threat to her enemies – and the line between Patience and her undomesticated alter ego begins to blur.